| MLB Statistics |
| Year: 2004 | 2005 | 2006 | 2007 | 2008 | Position: Hitters | Pitchers | C | 1B | 2B | SS | 3B | OF | DH |
| Leagues: MLB | AL | NL |
| 2008 Designated Hitters | |||||||||||||||||
| Rk | Name | Team | AB | R | H | 2B | 3B | HR | RBI | SB | CS | BB | K | Avg | OBP | SLG | OPS |
| 1. | Aubrey Huff | BAL | 323 | 49 | 90 | 25 | 1 | 17 | 53 | 2 | 0 | 31 | 48 | .279 | .344 | .520 | .864 |
| 2. | Jim Thome | CWS | 260 | 44 | 60 | 15 | 0 | 16 | 44 | 1 | 0 | 46 | 78 | .231 | .352 | .473 | .825 |
| 3. | Milton Bradley | TEX | 256 | 51 | 82 | 22 | 0 | 17 | 54 | 4 | 2 | 49 | 67 | .320 | .434 | .605 | 1.039 |
| 4. | Jason Kubel | MIN | 255 | 43 | 68 | 9 | 3 | 12 | 43 | 0 | 1 | 24 | 47 | .267 | .325 | .467 | .792 |
| 5. | Hideki Matsui | NYY | 251 | 37 | 81 | 13 | 0 | 7 | 34 | 0 | 0 | 31 | 30 | .323 | .404 | .458 | .862 |
| 6. | Jose Vidro | SEA | 240 | 23 | 52 | 9 | 0 | 5 | 37 | 1 | 1 | 16 | 31 | .217 | .264 | .317 | .581 |
| 7. | Matt Stairs | TOR | 217 | 31 | 56 | 8 | 0 | 8 | 28 | 1 | 1 | 25 | 54 | .258 | .340 | .406 | .746 |
| 8. | David Ortiz | BOS | 210 | 36 | 53 | 10 | 0 | 13 | 43 | 0 | 0 | 33 | 37 | .252 | .354 | .486 | .840 |
| 9. | Gary Sheffield | DET | 182 | 23 | 41 | 9 | 0 | 5 | 18 | 3 | 0 | 29 | 40 | .225 | .338 | .357 | .695 |
| 10. | Travis Hafner | CLE | 157 | 19 | 34 | 9 | 0 | 4 | 22 | 1 | 1 | 23 | 44 | .217 | .326 | .350 | .676 |
| 11. | Frank Thomas | TOR/OAK | 151 | 19 | 39 | 5 | 1 | 7 | 27 | 0 | 0 | 26 | 33 | .258 | .372 | .444 | .816 |
| 12. | Cliff Floyd | TB | 111 | 15 | 28 | 4 | 0 | 6 | 16 | 1 | 0 | 15 | 28 | .252 | .344 | .450 | .794 |
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